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Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)
IMSI is a new technique that allows a better selection of the sperm that is going to be micro-injected. It uses ultra-high magnification to allow greater visualisation of the structure of the sperm. IMSI is suitable for patients with recurrent miscarriage or those where sperm morphology is particularly poor. The technique is identical to the ICSI procedure, the only difference being the way the sperm are chosen. IMSI is the latest development for male factor infertility.
Why IMSI can help?
Achieving a healthy pregnancy is hugely dependent on the quality of the human embryo. The quality of an embryo is a product of the quality of the egg and the quality of the sperm that fertilises the egg. Many sperm and eggs have abnormalities that can create an embryo which is unlikely to implant and become a successful pregnancy.
Some sperm abnormalities can be identified using a normal microscope which magnifies 200 – 400 times. With IMSI a microscope is used that can magnify up to 6000 times. This allows embryologists to see any abnormalities in the head of the sperm. By selecting sperm without abnormalities, the chance of creating better quality embryos is improved. This should hopefully result in a higher chance of pregnancy and lower chance of miscarriage for the patient.
The doctor will decide whether you are eligible for IMSI if you meet any one of the below criteria:
- The male partner is over 35.
- Two failed ICSI cycles.
- Three failed IVF cycles.
- Over 90% abnormal forms in sperm.
- Only if the patient has sufficient motile sperm for selection.
Please note that even if you meet one of these criteria, you may be excluded if there are insufficient numbers of motile sperm in the sample on the day of egg collection. If this occurs on the day of egg collection, doctor will discuss the implications with you.
Success Rates with IMSI
There are many factors that contribute to the success of IMSI, including the experience of the doctor performing the procedure, the health of the patient’s eggs, and the quality of the sperm. However, IMSI has a very high success rate when performed by an experienced doctor using high-quality sperm and eggs. One study found that the pregnancy rate with IMSI was 73% when using fresh sperm, and 66% when using frozen sperm. Another study found that IMSI resulted in a clinical pregnancy rate of 65%. These success rates are much higher than those achieved with other fertility treatments such as IVF.
Amrutha Fertility Center’s Role in IMSI Treatment
Intracytoplasmic morphologically selected sperm injection, or IMSI, is a type of in-vitro fertilization that uses a high-powered microscope to select the best sperm for injection into the egg. This procedure is often used when there are concerns about the quality of the sperm, such as low motility or abnormal morphology.
Amrutha Fertility Center offers IMSI treatment as part of our comprehensive IVF services. Our team of experienced fertility specialists will work with you to determine if IMSI is the right treatment for you. If so, we will carefully select the best sperm for injection and monitor your progress throughout the treatment.
IMSI can be an effective treatment for couples struggling with infertility, and Amrutha Fertility Center is proud to offer this option to our patients. If you would like to learn more about IMSI or our other fertility treatments, please contact us today.
FAQ's
How does IMSI work?
During IVF, the eggs are retrieved from the ovaries and fertilized with sperm in a lab dish. With IMSI, a high-powered microscope is used to examine the sperm and select only those that appear to be normal and healthy. These sperm are then injected into the eggs using a very thin needle.
What are the benefits of IMSI?
IMSI has been shown to improve pregnancy rates and decrease the risk of genetic abnormalities in the offspring. Additionally, IMSI may be beneficial for couples who have failed previous IVF cycles or who have a history of miscarriage.
How is IMSI performed?
Intracytoplasmic morphologically selected sperm injection (IMSI) is a type of in vitro fertilization (IVF). IMSI is a procedure in which a high-powered microscope is used to select the best sperm for injection into the egg.
Are there any risks associated with IMSI?
There are no known risks associated with IMSI. However, as with any medical procedure, there is always a slight risk of complications.